Results for the UK general election on 6 May 2010 South East, England - Elections won by Liberal Democrat
| Constituency | Candidate | Electorate | Turnout | Votes | Vote share | Vote change | Majority |
| Eastbourne | LLOYD, Stephen | 77,840 | 67.0% | 24,658 | 47.3% | +5.6% | 3,435 |
| Eastleigh | HUHNE, Chris | 77,436 | 69.3% | 24,966 | 46.5% | +8.2% | 3,864 |
| Lewes | BAKER, Norman | 68,708 | 72.9% | 26,048 | 52.0% | +0.5% | 7,647 |
| Portsmouth South | HANCOCK, Mike | 70,242 | 58.7% | 18,921 | 45.9% | +4.2% | 5,200 |
Turnout as calculated by the House of Commons Library, is the total number of votes cast and not spoiled, divided by the size of the electorate.
This was the first election on a new set of constituency boundaries in England, Northern Ireland and Wales. The vote share calculations in those countries are based on notional results, which estimate the outcome of the previous election had it been contested on the new boundaries.